Global leader in high content screening introduces latest version of
Columbus data storage and analysis system at 2012 High Content Analysis
Conference in San Francisco
WALTHAM, Mass.--(BUSINESS WIRE)--
PerkinElmer
Inc., a global leader focused on the health and safety of people and
the environment, will showcase the enhanced Columbus
2.3 Image Data Storage and Analysis System at the High
Content Analysis Conference in San Francisco. Researchers in the
areas of cancer and stem cells, predictive toxicity, neuroscience and
developmental biology can benefit from the improved capabilities of the
updated Columbus system, which are intended to enable faster and more
powerful high content analysis-based research applications.
The Columbus 2.3 platform now enables scientists to perform their high
content analysis on one powerful platform, from image analysis through
to secondary analysis, regardless of which high content screening (HCS)
instrument they have. The secondary analysis capabilities can enable
scientists to select small interfering RNA (siRNA) or compounds with
desirable inhibition or activation effects, by proving the statistical
significance of the observations made at the image analysis stage of a
high content screening campaign. Multiple plates or batches are
analyzed, filtering out anomalies and identifying trends.
The improved morphology analysis capability of the software is designed
to give scientists a more complete understanding of the effects
different treatments have on cell samples, adding to the Columbus
system's already extensive analysis tools that enable scientists to
analyze high content images acquired on any instrument.
The platform is designed to shorten high content analysis workflow and
ultimately accelerate research in disease, biology and drug discovery.
The updated system's new secondary analysis capabilities and improved
morphology analysis make the Columbus platform one of the only universal
high-volume image analysis and storage solutions commercially available
for high content screening. The Columbus system supports an extensive
range of image file formats for microscopy and screening with import
filters and through compliance with the Open Microscopy Environment
(OME).
"PerkinElmer understands how important data analysis is to our
customers. The Columbus system provides researchers with a single
solution for high content analysis that is designed to enable analysis
of data from all major HCS systems in a consistent way and compare the
cellular parameters, thereby leading to better quality and more
statistically relevant results," said Achim Von Leoprechting, vice
president and general manager, in-vitro solutions, PerkinElmer.
This latest version of the Columbus system features a further improved
version of PerkinElmer's unique machine-learning technology, PhenoLOGIC™,
which makes cell classification as easy as point-and-click. It also
includes changes to the user interface which make it similar to the
instrument control software for PerkinElmer's Operetta®
High Content Imaging and Opera®
High Content Screening Systems, intended to reduce time spent
training staff on the use of multiple software platforms.
About PerkinElmer, Inc.
PerkinElmer, Inc. is a global leader focused on improving the health and
safety of people and the environment. The Company reported revenue of
approximately $1.7 billion in 2010, has about 7,000 employees serving
customers in more than 150 countries, and is a component of the S&P 500
Index. Additional information is available through 1-877-PKI-NYSE, or at www.perkinelmer.com.

Edelman (on behalf of PerkinElmer, Inc.)
Amanda L. Connolly,
404-832-6785
amanda.connolly@edelman.com
Source: PerkinElmer, Inc.
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